PARSLEY, is a common feature in our salads, various stuffings, breakfast condiments and egg dishes. Tabbouleh, the traditional salad of Lebanon, is 60% Parsley. (Recipe Here)
This article was published by Ralph W. Moss, PhD, who has been writing about cancer — especially its less-conventional treatments — for over 35 years.
He has written/edited twelve books and three film documentaries on questions relating to cancer research and treatment. Moss is a graduate of New York University (BA, cum laude, Phi Beta Kappa, 1965) and Stanford University and a former science writer and assistant director of public affairs at Memorial Sloan-Kettering Cancer Center in New York.
SATURDAY, OCTOBER 31, 2015
In 1936, Albert Szent-Györgyi, MD, PhD, discovered a class of bioactive compounds that controlled hemorrhaging in certain medical conditions (Armentano 1936). These compounds are found in many plants, including his native Hungarian paprika and lemon juice. They were named bioflavonoids.
In recent years, attention has focused on one particular flavone called. There are now over 3,000 PubMed-indexed journal articles discussing apigenin.
…in September 2015 Sanjeev Shukla, PhD, of Case Western Reserve University, Cleveland wrote such an article. He and the Ohio scientists team found that apigenin effectively inhibited a molecule called IKKα.
.. IKKα is a “key driver of the metastatic process” and therefore a “promising therapeutic target in anticancer drug research.”
…they have now identified an effective inhibitor of this undesirable enzyme—APIGENIN!
Apigenin, they wrote,
“exhibits anticancer efficacy in experimental tumor model.”
In mice, apigenin stops tumor growth, lowers the proliferation rate of malignant cells and enhances apoptosis (the predominant form of programmed cell death). They identified some other anticancer effects:
- Causes cell cycle arrest in prostate cancer cells
- Suppresses migration in cancer cells
- Suppresses tumor growth in athymic nude mice
Apigenin and prostate cancer
“Accumulated evidence leads us to hypothesize that there is some distinct mechanism by which apigenin suppresses prostate cancer growth, and we believe this warrants further investigation.”
A small clinical trial was performed in Groß-Gerau, Germany, and published by Prof. Harald Hoensch. His group gave a food supplement of 10 milligrams (mg) of apigenin as well as 10 mg of EGCg (a main ingredient in green tea) to patients who had either colorectal cancer or premalignant polyps of the colon. The results were dramatic. In the control group, 47 percent (7 out of 15) had recurrences. But in the treated group, only 7 percent (1 out of 14) had a recurrence.
The Most Abundant Sources
- Dried Parsley leaves
According to one nutritional Web site (merschat.com), dried parsley has an incredible 13,000 mg per 100 grams. In other words, it is 13 percent apigenin by weight!
Fresh parsley has a considerable 225 to 300 mg per 100 grams.
Other good sources:
- raw celery
- also in chamomile flower tea
Put another way, one cup of chopped raw parsley has over 180 mg of apigenin. To get a 10 mg dose, as in the clinical trial, you would only need to take one tablespoon of raw chopped parsley per day. Alternately, you could sprinkle a small amount of dried parsley into your food.
The toxicity of apigenin consists of an occasional allergic reaction, or possibly an undesirable interactions with other drugs. There is, however, one laboratory study that seemed to show that although apigenin was effective at killing leukemia cells, it simultaneously interfered with one standard drug used in the chemotherapy of that same disease (Ruella-de-Sousa 2010). It thus might be wise to NOT take high doses of this chemical if you are currently undergoing chemotherapy for cancer.
At the very least you should discuss this with your oncologist. Most reasonable doctors would not object to you adding a tablespoon of parsley to your daily regimen. It could do a world of good.